Toxicological Properties of Specific Aromatic Hydrocarbons Isolated from Fresh and Aged Crude Oil from the Deepwater Horizon Spill


Project Overview

Implementing Organization
Tulane University School of Public Health and Tropical Medicine

DWH Project Funding

0

Known Leveraged Funding

0

Funding Organization

Gulf of Mexico Research Initiative (GoMRI)

Funding Program

Gulf of Mexico Research Initiative (GoMRI) Grant Program

Project Location: Louisiana

Funding Source: BP
Controlling Document: GOMRI Master Research Agreement
Year Awarded: 2016

Project Details

Project Category

Project Actions

Public Health Research

Targeted Resources

Human and / or Institutional Capacity Petroleum

Project Description

Oil spills are well recognized for causing toxic effects in people and environmental organisms. However, oil is chemically complex and the specific compounds that contribute to its toxicity are surprisingly poorly defined. Specifically, petrogenic polycyclic aromatic hydrocarbons (PAHs) are a large family of chemicals in oil that have never been evaluated for toxicity. We will identify highly toxic compounds within fresh and weathered oil samples using a marriage of analytical chemical methodologies and cellular bioassays. This process will identify the presence and relative potencies of PAHs and structurally related chemicals that activate the aryl hydrocarbon receptor (AhR). Activation of AhR is the key initial step in a signaling pathway that ultimately results in toxicity. Our goal is to use these identified toxic compounds as a gauge of toxicity for any fresh or aged oil sample.

Project Contact

Project Partners

None

Affiliated Institutions

Louisiana State University


Project ID: 516
Project Name: Toxicological Properties of Specific Aromatic Hydrocarbons Isolated from Fresh and Aged Crude Oil from the Deepwater Horizon Spill
SourceUID: 280
Latitude: 29.956874
Longitude: -90.075402
Country: United States of America
State or Province: Louisiana
County: Orleans
Project Category: Science
Project Action: Public Health Research
Additional Project Action(s):
Additional Project Action(s):
Targeted Resource(s): Human and/or Institutional Capacity
Targeted Resource(s): Petroleum
Targeted Resource(s):
Anticipated Project Completion Year: 2018
Implementing Organization: Tulane University School of Public Health and Tropical Medicine
Implementing Organization Type: Academic
Point of Contact – Name: Charles Miller
Point of Contact – Phone: rellim@tulane.edu
Point of Contact – Email: None
Other Partners: None
Affiliated Institutions: Louisiana State University
Link: http://research.gulfresearchinitiative.org/research-awards/projects/?pid=280
Project Comments: None
Acres Acquired: 0
Close Year: 0
Close Month: 0
Close day: 0
Purchase Type: None
Landowner: None
Landowner Type: None
Purpose: None
Public Access: None
Easement Holder Name : None
Easement Holder Type: None
Secondary Easement Holder 1: None
Secondary Easement Holder 2: None
Duration: None
Term: 0
Land Restoration Acreage: 0
Aquatic Restoration Acreage: 0
Restoration Mileage: 0
Restoration Feet: 0
Additional Acreage: None
Total Dollar Amount (from all funders): 1574110
DWH Funder: Gulf of Mexico Research Initiative (GoMRI)
DWH Funder Type: Private
DWH Funding Program: Gulf of Mexico Research Initiative (GoMRI) Grant Program
DWH Dollar Amount : 1574110
DWH Source: BP
Fund Origin: Voluntary Agreement
Controlling Documents: GOMRI Master Research Agreement
Award Year: 2016
Award Month: 1
Total Amount Leveraged: 0