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Chemical Dispersants in the Marine Environment: Harnessing the Fish Acute Phase Response for Rapid and Sensitive Evaluation of Exposure

Implementing Organization

University of Alabama at Birmingham


DWH Project Funding


Known Leveraged Funding


Funding Organization

Gulf of Mexico Research Initiative (GoMRI)

Funding Program

Gulf of Mexico Research Initiative GoMRI Grant Program


Project Category


Project Actions

Environmental Research

Targeted Resources

Human and/or Institutional Capacity

Project Description

Toxicity of crude oil and chemical agents used in clean-up and remediation is generally gauged by calculation of the LC50 (concentration required to kill 50% of exposed indicator species in a specified time period); nevertheless, even low non-lethal levels of chemical by-products can negatively impact animal health and well-being. The sub-lethal effects of these chemicals on growth, development, and reproduction are important to consider when assessing the full environmental impact of pollutants at the organismal level.


Stephen Watts
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